Adolescent and Parent Perceptions about Participation in Biomedical Sexual Health Trials.
Adolescent and Parent Perceptions about Participation in Biomedical Sexual Health Trials.
复制标题
青少年和家长对参与生物医学性健康试验的看法。
DOI：
10.1002/eahr.500048
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发表时间：
2020
影响因子：
--
通讯作者：
Rosenthal,SusanL
中科院分区：
文献类型：
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作者：
Landers,SaraE;Francis,JennyKR;Morris,MarilynC;Mauro,Christine;Rosenthal,SusanL
鉴于法定未成年人感染艾滋病毒和其他性传播感染的负担，至关重要的是，必须将他们纳入性健康生物医学试验，以确保新的预防和治疗干预措施的使用安全、有效和可接受。然而，青少年在临床试验中往往没有得到很好的代表。我们概述了关于青少年和父母参与生物医学性健康试验的意愿、父母在许可-同意过程中的参与、青少年和父母之间的分歧和不和谐的管理以及父母在整个研究期间的参与的现有证据。我们还概述了对当前实践和未来研究领域的建议。
Given the burden of HIV and other sexually transmitted infections among adolescents who are legal minors, it is critical that they be included in biomedical sexual health trials to ensure that new prevention and treatment interventions are safe, effective, and acceptable for their use. However, adolescents are often not well represented in clinical trials. We provide an overview of the available evidence regarding adolescent and parent willingness for adolescents to participate in biomedical sexual health trials, parental involvement in the permission‐consent process, management of differences and discord among adolescents and parents, and parental involvement throughout the study period. We also outline recommendations for current practice and areas for future research.