Hay fever, eczema, and wheeze: a nationwide UK study (ISAAC, international study of asthma and allergies in childhood)
Hay fever, eczema, and wheeze: a nationwide UK study (ISAAC, international study of asthma and allergies in childhood)
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DOI：
10.1136/adc.81.3.225
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发表时间：
1999-09-01
影响因子：
5.2
通讯作者：
Warner, JO
中科院分区：
文献类型：
--
作者：
Austin, JB;Kaur, B;Warner, JO
目的-描述特应性症状在整个英国儿童中的患病率。方法-使用国际儿童哮喘和过敏研究(ISAC)方案，对英格兰、威尔士、苏格兰和苏格兰群岛的12-14岁儿童进行问卷调查。结果-共有27 507名儿童(86%)参与调查。最近的鼻结膜炎的报告比例为18.2%，其中6.2%的患者报告在3月至9月期间出现症状；16.4%的患者报告在过去12个月中出现瘙痒的屈曲皮疹。在英国出生的女孩和受试者中，特应性症状的患病率更高。严重喘息的发生率在报告常年性鼻结膜炎的受试者中最高，而不是仅在夏季才有症状。冬季鼻结膜炎伴有严重的喘息和严重的屈曲皮疹。47.6%的儿童报告了一种或多种当前症状，4%的儿童报告了所有三种症状。结论--总的来说，地理差异很小，但在苏格兰和英格兰北部，症状的患病率明显较高。这项研究证明了特应性疾病本身以及与哮喘相关的重要性。
Objectives-To describe the prevalence of atopic symptoms in children throughout the UK.Method-A questionnaire survey of 12-14 year olds throughout England, Wales, Scotland, and the Scottish Islands using the international study of asthma and allergies in childhood (ISAAC) protocol.Results-A total of 27 507 (86%) children took part. Recent rhinoconjunctivitis was reported by 18.2%, with 6.2% reporting symptoms between March and September; 16.4% reported itchy flexural rash in the past 12 months. The prevalence of atopic symptoms was higher in girls and subjects born within the UK. The prevalence of severe wheeze was highest in subjects reporting perennial rhinoconjunctivitis, as opposed to summertime only symptoms. Winter rhinoconjunctivitis was associated with severe wheeze and severe flexural rash. One or more current symptoms were reported by 47.6% of all children and 4% reported all three symptoms.Conclusion-In general, geographical variations were small but the prevalence of symptoms was significantly higher in Scotland and northern England. The study demonstrates the importance of atopic diseases both in their own right and in association with asthma.