MUTISM AND AUDITORY AGNOSIA DUE TO BILATERAL INSULAR DAMAGE - ROLE OF THE INSULA IN HUMAN-COMMUNICATION
MUTISM AND AUDITORY AGNOSIA DUE TO BILATERAL INSULAR DAMAGE - ROLE OF THE INSULA IN HUMAN-COMMUNICATION
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DOI：
10.1016/0028-3932(94)00108-2
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发表时间：
1995-03-01
期刊：
影响因子：
2.6
通讯作者：
KHALIL, R
中科院分区：
文献类型：
--
作者：
HABIB, M;DAQUIN, G;KHALIL, R
我们报告一个短暂性缄默症和持续性听觉失认症的病例，由于两个连续的缺血性梗塞，主要涉及两个半球的岛叶皮层。在持续约1个月的“沉默”期间，患者对任何听觉刺激没有反应，也没有努力进行交流。在后续检查中，语言能力几乎完好无损地重新出现，但观察到对非语言声音的大量听觉失认症。从密切检查病变部位，确定与脑共振成像，并从听觉诱发电位的研究，它的结论是，双边岛叶损伤是至关重要的表达和接受组件的综合征。在口头和非口头交流的作用的大脑皮层的岛叶皮层的连接模式的解剖学描述的光进行了讨论。
We report a case of transient mutism and persistent auditory agnosia due to two successive ischemic infarcts mainly involving the insular cortex on both hemispheres. During the 'mutic' period, which lasted about 1 month, the patient did not respond to any auditory stimuli and made no effort to communicate. On follow-up examinations, language competences had re-appeared almost intact, but a massive auditory agnosia for non-verbal sounds was observed. From close inspection of lesion site, as determined with brain resonance imaging, and from a study of auditory evoked potentials, it is concluded that bilateral insular damage was crucial to both expressive and receptive components of the syndrome. The role of the insula in verbal and non-verbal communication is discussed in the light of anatomical descriptions of the pattern of connectivity of the insular cortex.