Triethanolamine as an efficient and reusable base, ligand and reaction medium for phosphane-free palladium-catalyzed Heck reactions
Triethanolamine as an efficient and reusable base, ligand and reaction medium for phosphane-free palladium-catalyzed Heck reactions
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DOI：
10.1002/ejoc.200600561
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发表时间：
2006-11-13
影响因子：
2.8
通讯作者：
Wang, Lei
中科院分区：
文献类型：
--
作者：
Li, Hong Ji;Wang, Lei
三乙醇胺是一种高效、可重复使用的碱、配体和反应介质，用于无膦钯催化的Heck反应。在没有任何添加剂的情况下，在三乙醇胺中催化量的醋酸钯存在下，碘代芳烃和溴代芳烃的烯化反应以良好到优异的产率生成相应的产物。用活化的氯代芳烃得到了所需产物的中等产率。此外，三乙醇胺可以连续回收和再循环五次，而不会显著损失其反应性。((C)Wiley-VCH Verlag GmbH&Co.KGaA，69451 Weinheim，德国)
Triethanolamine was found to be an efficient and reusable base, ligand and reaction medium for phosphane-free palladium-catalyzed Heck reactions. The olefination of iodo- and bromoarenes generated the corresponding products in good to excellent yields in the presence of catalytic amounts of palladium acetate in triethanolamine without any additive. Moderate yields of the desired products were obtained with activated chloroarenes. In addition, triethanolamine could be recovered and recycled for five consecutive trials without significant loss of its reactivity. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)