Expression of Rat Sperm Flagellum-Movement Associated Protein Genes under 2,3,7,8-Tetrachlorodibenzo-p-dioxin Treatment
Expression of Rat Sperm Flagellum-Movement Associated Protein Genes under 2,3,7,8-Tetrachlorodibenzo-p-dioxin Treatment
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2,3,7,8-四氯二苯并-对二恶英处理下大鼠精子鞭毛运动相关蛋白基因的表达
DOI：
10.1271/bbb.80764
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
K. Ohyama
中科院分区：
文献类型：
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作者：
Y. Yamano;A. Asano;M. Ohta;S. Hirata;T. Shoda;K. Ohyama
我们分析了精子鞭毛运动相关蛋白，即腺苷酸激酶结构域蛋白（RGD1303144）和外致密纤维蛋白1的基因表达。这些基因在成熟大鼠睾丸中表达上调，RGD1303144基因在精母细胞中主要表达。尽管2,3,7,8-四氯二苯并-对二恶英降低了精子活力，但这些基因的表达并未受到影响。
We analyzed the gene expression of sperm flagellum-movement associated proteins, namely, adenylate kinase domain containing protein (RGD1303144) and outer dense fiber protein 1. These gene expressions were up-regulated in a maturing rat testis, and RGD1303144 gene was expressed dominantly in spermatocytes. Although 2,3,7,8-tetrachlorodibenzo-p-dioxin administration reduced sperm motility, these gene expressions were not affected.