Long-term follow-up of patients with thalamic deep brain stimulation for epilepsy
Long-term follow-up of patients with thalamic deep brain stimulation for epilepsy
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DOI：
10.1212/01.wnl.0000206364.19772.39
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发表时间：
2006-05-23
期刊：
影响因子：
9.9
通讯作者：
Wennberg, R. A.
中科院分区：
文献类型：
--
作者：
Andrade, D. M.;Zumsteg, D.;Wennberg, R. A.
作者描述了长期随访（平均5年）对接受前（n = 6）或中位（n = 2）丘脑深部脑刺激（DBS）治疗癫痫的患者。5例患者（均为AN）癫痫发作减少>= 50%，但在改变抗癫痫药物后，获益延迟了2年，直到第5至6年。AN患者DBS电极植入后，在主动刺激前1至3个月癫痫发作减少，提高了有益的小丘脑切除术效果的可能性。
The authors describe long-term follow-up (mean, 5 years) in patients with anterior (AN) (n = 6) or centromedian (n = 2) thalamic deep brain stimulation (DBS) for epilepsy. Five patients (all AN) had >= 50% seizure reduction, although benefit was delayed in two until years 5 to 6, after changes in antiepileptic drugs. DBS electrode implantation in AN patients was followed by seizure reduction 1 to 3 months before active stimulation, raising the possibility of a beneficial microthalamotomy effect.