Adult retinal pigment epithelial transplantation in exudative age-related macular degeneration
Adult retinal pigment epithelial transplantation in exudative age-related macular degeneration
复制标题
DOI：
10.1016/j.ajo.2006.12.007
复制
发表时间：
2007-04-01
影响因子：
4.2
通讯作者：
Kaplan, Henry J.
中科院分区：
文献类型：
--
作者：
Tezel, Tongalp H.;Del Priore, Lucian V.;Kaplan, Henry J.
目得：目的：探讨在渗出性老年性黄斑变性（AMD）患者行黄斑中心凹下脉络膜新生血管切除术时，行视网膜色素上皮（RPE）细胞移植和全身免疫抑制治疗，以改善患者的视功能AMD.center。12名患者（仅一只眼睛）在一个机构接受了中心凹下膜切除术，移植了一片成人同种异体RPE细胞，并随访了一年。资格标准包括年龄> 60岁、最佳、矫正视力
PURPOSE: To improve visual function by retinal pig, ment epithelial (RPE) cell transplantation and systemic immunosuppression at the time of surgical removal of subfoveal choroidal neovascularization in exudative agerelated macular degeneration (AMD).center dot DESIGN: An interventional case series of RPE transplantation in exudative AMD.center dot METHODS: Twelve patients (one eye only) underwent subfoveal membranectomy with transplantation of a sheet of adult human allogeneic RPE cells at a single institution and were followed for one year. Eligibility criteria included age > 60, best,corrected acuity