Application of thin film transistors to label-free electrical biosensors
Application of thin film transistors to label-free electrical biosensors
复制标题
薄膜晶体管在无标记电生物传感器中的应用
DOI：
10.1109/isie.2008.4677045
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
P. Migliorato
中科院分区：
文献类型：
--
作者：
P. Estrela;S. Keighley;P. Li;P. Migliorato
生物技术迫切需要低成本的智能生物芯片，以使用便携式仪器大规模并行检测生物分子相互作用。实现这一目标的一种方法是利用成熟的半导体技术来开发生物传感器阵列。特别是薄膜晶体管技术，可以在这个迅速发展的领域发挥重要作用。TFT既可以作为检测不同生物分子相互作用的电位传感器，也可以作为电路元件，用于调节和读出有前途的无标记电子检测技术的信号，如电化学阻抗谱。
Biotechnology is in great need of low-cost intelligent biochips for massive parallel detection of biomolecular interactions, using portable instrumentation. One way this may be achieved is to exploit mature semiconductor technologies for the development of biosensor arrays. Thin film transistor technology in particular can play an important role in this rapidly expanding field. TFTs can be applied either as potentiometric sensors for the detection of different biomolecular interactions or as circuit elements for conditioning and read-out of signals of promising label free electrical detection techniques such as electrochemical impedance spectroscopy.