Three-Dimensional Paper Microfluidic Devices Assembled Using the Principles of Origami
Three-Dimensional Paper Microfluidic Devices Assembled Using the Principles of Origami
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DOI：
10.1021/ja2071779
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发表时间：
2011-11-09
影响因子：
15
通讯作者：
Crooks, Richard M.
中科院分区：
文献类型：
--
作者：
Liu, Hong;Crooks, Richard M.
我们报告了一种基于折纸（纸张折叠）原理的方法，用于制造三维（3-D）纸张微流体装置。整个 3D 设备通过单个光刻步骤在单张平板纸上制造而成。只需用手折叠纸张即可组装。分析完成后，可以展开设备以显示每一层。使用多层微流体网络的比色和荧光测定证明了该装置在化学分析中的适用性。
We report a method, based on the principles of origami (paper folding), for fabricating three-dimensional (3-D) paper microfluidic devices. The entire 3-D device is fabricated on a single sheet of flat paper in a single photolithographic step. It is assembled by simply folding the paper by hand. Following analysis, the device can be unfolded to reveal each layer. The applicability of the device to chemical analysis is demonstrated by colorimetric and fluorescence assays using multilayer microfluidic networks.