Effects of dietary fatty acid composition on 24-h energy expenditure and chronic disease risk factors in men
Effects of dietary fatty acid composition on 24-h energy expenditure and chronic disease risk factors in men
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DOI：
10.3945/ajcn.2008.27419
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发表时间：
2009-05-01
影响因子：
7.1
通讯作者：
Schoeller, Dale A.
中科院分区：
文献类型：
--
作者：
Cooper, Jamie A.;Watras, Abigail C.;Schoeller, Dale A.
背景：高脂肪（HF）饮食和久坐不动的生活方式与肥胖的发生有关。控制喂养研究和短期静息能量消耗（REE）的测量表明，膳食脂肪的类型可能会改变能量消耗（EE）。目的：目的是检查富含单不饱和或饱和脂肪酸（FAs）的HF饮食和运动对EE和慢性疾病危险因素的影响。体重指数（kg/m2）：22 +/- 3]在2 × 2交叉设计中随机分配到4个处理中的1个：HF饮食（50%的能量）与大量的饱和脂肪（22%的能量）加运动（SE）或久坐（SS）条件或高单不饱和脂肪（30%的能量）饮食加运动（UE）或久坐（US）条件。受试者在代谢室中度过5天，在运动访问期间每天以45%的最大摄氧量循环2小时。分别于第2、4、6天测定24 h呼气末容积（EE）和静息代谢率（RE）。平均24小时EE没有不同方面的饮食FA组成（SE、UE、SS和US分别为3202 +/- 146、3208 +/- 151、2240 +/- 82和2270 +/- 104）。总胆固醇和低密度脂蛋白胆固醇和血压显着更大的SE和SS治疗后比UE和US treatment.Conclusion：休息代谢率和24小时EE短期暴露后，HF饮食中富含单不饱和脂肪酸或暴露后，在健康，非肥胖男性的饮食中富含饱和脂肪酸没有显着差异。美国临床营养杂志2009;89：1350-6。
Background: A high-fat (HF) diet and sedentary lifestyle are implicated in the development of obesity. Controlled feeding studies and measures of short-term resting energy expenditure (REE) have suggested that the type of dietary fat may alter energy expenditure (EE).Objective: The objective was to examine the effects of an HF diet rich in either monounsaturated or saturated fatty acids (FAs) and of exercise on EE and chronic disease risk factors.Design: Eight healthy men [age: 18-45 y; body mass index (in kg/m(2)): 22 +/- 3] were randomly assigned in a 2 x 2 crossover design to 1 of 4 treatments: HF diet (50% of energy) with a high amount of saturated fat (22% of energy) plus exercise (SE) or a sedentary (SS) condition or a diet high in monounsaturated fat (30% of energy) plus exercise (UE) or a sedentary (US) condition. The subjects spent 5 d in a metabolic chamber and cycled at 45% of maximal oxygen uptake for 2 h each day during the exercise visits. Respiratory gases and urinary nitrogen were measured to determine 24-h EE. Resting metabolic rate was measured on days 2, 4, and 6.Results: Average 24-h EE was not different with respect to dietary FA composition (3202 +/- 146, 3208 +/- 151, 2240 +/- 82, and 2270 +/- 104 for SE, UE, SS, and US, respectively). Total and LDL cholesterol and blood pressure were significantly greater after the SE and SS treatments than after the UE and US treatments.Conclusion: Resting metabolic rate and 24-h EE were not significantly different after short-term exposure to an HF diet rich in monounsaturated FAs or after exposure to a diet rich in saturated FAs in healthy, nonobese men. Am J Clin Nutr 2009;89:1350-6.