Encoding schemes in somatosensation: From micro- to meta-topography
Encoding schemes in somatosensation: From micro- to meta-topography
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DOI：
10.1016/j.neuroimage.2020.117255
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发表时间：
2020-12-01
期刊：
影响因子：
5.7
通讯作者：
Pleger, Burkhard
中科院分区：
文献类型：
--
作者：
Kuehn, Esther;Pleger, Burkhard
编码方案是将传入的感觉信息转换为进一步信息处理所需的格式的系统化大规模安排。使用7T及以上超高场磁共振成像(7T-MRI)获得的脑图像的空间分辨率提高，提高了参与神经元编码和功能读出之间联系的处理单元的粒度和精度。在这里，这些新的发展被重点放在从小规模的处理单元(大约0.5-5毫米)派生的人类触觉编码方案，它与躯体感觉编码和皮质可塑性的理论和实践概念相关。确切地说，我们回顾了最近描述活体人脑感觉运动皮质中的中尺度地图、层单元和皮质场的方法，并讨论了它们对知觉、运动控制、地形编码和皮质可塑性理论的影响。最后，我们讨论了将小规模处理单元集成到跨越多个地形图和多个皮质区域的功能网络的概念。新的研究领域被强调，可能有助于弥合大脑解剖和功能上的皮质微结构和元地形模型之间的差距。
Encoding schemes are systematic large-scale arrangements that convert incoming sensory information into a format required for further information processing. The increased spatial resolution of brain images obtained with ultra-high field magnetic resonance imaging at 7 T (7T-MRI) and above increases the granularity and precision of processing units that mediate the link between neuronal encoding and functional readouts. Here, these new developments are reviewed with a focus on human tactile encoding schemes derived from small-scale processing units (in the order of 0.5-5 mm) that are relevant for theoretical and practical concepts of somatosensory encoding and cortical plasticity. Precisely, we review recent approaches to characterize meso-scale maps, layer units, and cortical fields in the sensorimotor cortex of the living human brain and discuss their impact on theories of perception, motor control, topographic encoding, and cortical plasticity. Finally, we discuss concepts on the integration of small-scale processing units into functional networks that span multiple topographic maps and multiple cortical areas. Novel research areas are highlighted that may help to bridge the gap between cortical microstructure and meta-topographic models on brain anatomy and function.