Formaldehyde exposure, acute pulmonary response, and exposure control options in a gross anatomy laboratory.
Formaldehyde exposure, acute pulmonary response, and exposure control options in a gross anatomy laboratory.
复制标题
大体解剖实验室中的甲醛暴露、急性肺部反应和暴露控制选项。
DOI：
10.1002/ajim.4700260106
复制
发表时间：
1994
影响因子：
3.5
通讯作者：
Michael S. Bisesi
中科院分区：
文献类型：
--
作者：
Farhang Akbar;M. Ulises Vaquerano;Mahboubeh Akbar;Michael S. Bisesi
在大体解剖实验室的34名工人中，对甲醛暴露、急性肺反应和暴露控制方案进行了评估。在解剖手术期间，甲醛暴露的时间加权平均值(TWA)在0.07-2.94 ppm之间。超过94%的人暴露在甲醛中，超过了美国政府工业卫生师会议(ACGIH)建议的0.3ppm的上限。31.7%的受试者8小时的TWA暴露超过了美国职业安全与健康管理局(OSHA)设定的0.5ppm的行动水平。报告的症状包括眼睛(88%)、鼻子(74%)、喉咙(29%)和呼吸道(21%)。暴露期间用力肺活量(FVC)和3秒用力呼气量(FEV3)下降，FEV1/FVC升高。FEV3的变化与对照组比较差异有统计学意义。这些结果有力地支持了设计和测试具有解剖手术所需灵活性的特殊局部排气通风工作台的必要性。
Formaldehyde exposure, acute pulmonary response, and exposure control options were evaluated in a group of 34 workers in a gross anatomy laboratory. Time-weighted average (TWA) exposure to formaldehyde ranged from 0.07-2.94 parts per million (ppm) during dissecting operations. More than 94% were exposed to formaldehyde in excess of the ceiling value of 0.3 ppm recommended by the American Conference of Governmental Industrial Hygienists (ACGIH). The eight-hour TWA exposure of 31.7% of the subjects exceeded the action level of 0.5 ppm set by the Occupational Safety and Health Administration (OSHA). Reported symptoms included irritation of eye (88%), nose (74%), throat (29%), and airways (21%). Forced vital capacity (FVC) and forced expiratory volume in 3 seconds (FEV3) decreased, and FEV1/FVC increased during the exposure. The changes of FEV3 were statistically different from those of the controls. The results strongly support the necessity for designing and testing special local exhaust-ventilated worktables with necessary flexibility for dissecting operations.