Development of a three-dimensional jaw-tracking system implanted in the freely moving mouse
Development of a three-dimensional jaw-tracking system implanted in the freely moving mouse
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DOI：
10.1016/s1350-4533(01)00038-8
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发表时间：
2001-04-01
影响因子：
2.2
通讯作者：
Yamada, Y
中科院分区：
文献类型：
--
作者：
Koga, Y;Yoshida, N;Yamada, Y
设计了一种高分辨率的下颌骨跟踪系统，并在自由移动的小鼠中进行了测试。一个传感器单元，其中包括四个小的磁传感器，被用来跟踪小磁铁在三维空间中的运动。在从预实验校准数据的多元回归分析获得传感器的输出到位移的转换方程之后，将磁体和传感器转移到小鼠，使其保持在与校准系统中确定的相同配置。为了测量三维下颌运动，将磁体粘在小鼠的下颌表面上，并将传感器单元植入鼻骨中。利用传感器的输出-位移转换方程对传感器输出的电信号进行补偿，得到下颌运动轨迹。这种传感器系统，适用于自由移动的鼠标，可以跟踪下颌轨迹的精度优于20妈妈在三维空间。从而获得了小鼠咀嚼时下颌节律性运动的典型模式。小鼠在开颌期将下颌骨前伸至最前位置，在闭颌期将下颌骨后缩至最后位置，该跟踪系统也可应用于其它小型动物。(C)2001年妇女平等研究所。由爱思唯尔科技有限公司出版。保留所有权利。
A high-resolution mandibular tracking system was designed and tested in a freely moving mouse. A sensor unit, which consisted of four small magnetic sensors, was employed to trace small magnet movements in the three-dimensional space. After the sensor's output-to-displacement transformation equations were obtained from a multiple regression analysis of pre-experimental calibration data, the magnet and the sensors were transferred to the mouse, bring kept at the same configuration as determined in the calibration system. In order to measure the three-dimensional jaw movements, the magnet was glued on the mandibular surface of the mouse and the sensor unit was implanted in the nasal bone. Jaw-movement trajectories were obtained as electrical signals from the sensors after being compensated by the output-to-displacement transformation equations of the sensors with a personal computer. This sensor system, applied to the Freely moving mouse, could trace the jaw trajectories with an accuracy of better than 20 mum in three-dimensional space. Consequently, the typical pattern of the rhythmical jaw movements of the mouse during mastication was obtained. The mouse protruded the mandible to the most anterior position in the jaw-opening phase and retruded to it the most posterior position in the jaw-closing phase.This tracking system may also be applied to other small animals. (C) 2001 IPEM. Published by Elsevier Science Ltd. All rights reserved.