Establishment of a normal reference range for alpha 1-antitrypsin in Saudis using rate nephelometry.
Establishment of a normal reference range for alpha 1-antitrypsin in Saudis using rate nephelometry.
复制标题
使用速率比浊法建立沙特人 α1-抗胰蛋白酶的正常参考范围。
DOI：
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发表时间：
1988
影响因子：
3.1
通讯作者：
A. Warsy
中科院分区：
文献类型：
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作者：
S. Sedrani;S. I. El;A. Warsy
采用速率散射比浊法对543名健康男性和603名健康女性的α 1-抗胰蛋白酶水平进行了估计，以建立沙特人的“正常参考范围”。一个显着更高的平均值和范围内遇到的女性比男性，并获得α 1-抗胰蛋白酶水平和年龄之间的正相关性。由于α 1-抗胰蛋白酶显示正偏态分布，因此使用第2.5 - 97.5百分位数值确定正常参考范围。这篇文章介绍了α 1-抗胰蛋白酶的正常参考范围，10岁以下儿童为100至250 mg/dl，成年男性为95至275 mg/dl，成年女性为100至350 mg/dl。结果进行了讨论，在与其他地方报告的结果和试剂盒的制造商相比，遇到的显着差异。
Alpha 1-antitrypsin level was estimated in 543 healthy males and 603 healthy females using rate nephelometry, in order to establish a "normal reference range" in Saudis. A significantly higher mean and range were encountered in the females than in the males, and a positive correlation was obtained between the alpha 1-antitrypsin level and age. Since alpha 1-antitrypsin showed a positively skewed distribution, the normal reference ranges were established using the 2.5th to 97.5th percentile values. This article presents the normal reference range for alpha 1-antitrypsin as 100 to 250 mg/dl in children under 10 years of age, 95 to 275 mg/dl in adult males and 100 to 350 mg/dl in adult females. The results are discussed in light of the significant differences encountered in comparison with the results reported elsewhere and by the manufacturers of the kits.