The effect of the surface coverage of the phosphonic acid terminated self-assembled monolayers on the electrochemical behavior of dopamine.
The effect of the surface coverage of the phosphonic acid terminated self-assembled monolayers on the electrochemical behavior of dopamine.
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DOI：
10.1016/j.talanta.2010.01.063
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发表时间：
2010-05
期刊：
影响因子：
6.1
通讯作者：
Min Zheng;Y. Chen;Yiming Zhou;Yawen Tang;T. Lu
中科院分区：
文献类型：
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作者：
Min Zheng;Y. Chen;Yiming Zhou;Yawen Tang;T. Lu
巯基丙基膦酸（HS-CH_2CH_2CH_2-PO_3 H_2，MPPA）自组装膜在金表面的表面覆盖度可以通过调节溶液中膦酸基团（-PO_3 H_2）的解离程度和MPPA分子在碱性条件下的吸附时间来控制。电化学测试表明，低密度MPPA-SAMs修饰的金电极显著增强了多巴胺（DA）的电子转移动力学，提高了修饰电极对DA氧化的抑制能力。本研究结果为DA电化学传感器的设计和优化提供了重要信息。
The surface coverage of 3-mercaptopropylphosphonic acid (HS–CH2CH2CH2–PO3H2, MPPA) self-assembled monolayers (SAMs) on gold surface can be controlled by the dissociation degree of phosphonic acid groups (–PO3H2) in the bulk solution and adsorption time of MPPA molecules under the basic condition. Electrochemical measurements show that the low-density MPPA-SAMs modified gold electrode enhances significantly the kinetics of electron transfer of dopamine (DA), and improves the antifouling capability of modified electrode towards DA oxidation. The present results offer crucial information for design and optimization of the electrochemical sensors for DA determination.