Association between displacement and thickness of macula after vitrectomy in eyes with epiretinal membrane
Association between displacement and thickness of macula after vitrectomy in eyes with epiretinal membrane
复制标题
DOI：
10.1038/s41598-020-70197-6
复制
发表时间：
2020-08-06
影响因子：
4.6
通讯作者：
Terasaki, Hiroko
中科院分区：
文献类型：
--
作者：
Momota, Ayana;Iwase, Takeshi;Terasaki, Hiroko
本横断面回顾性研究的目的是确定玻璃体切除术联合内界膜（ILM）剥离后视网膜前膜（ERM）眼的视网膜位移与视网膜厚度之间的关系。为了实现这一点，我们使用光学相干断层扫描术（OCT）测量视网膜厚度，并使用OCT血管造影术测量视网膜位移，以获得20名患者的20只眼睛在手术前、术后2周、4周和8周的3 mm x 3 mm正面图像。术后4个象限内视网膜血管分叉点与中心凹的距离均明显离心移位，且不对称（P < 0.001）。术后中心凹无血管区（FAZ）明显扩大，中心凹厚度（CFT）和内核层（INL）厚度明显变薄。位移与FAZ面积（r = 0.717，P < 0.001）、CFT（r =-0.702，P < 0.001）和INL厚度（r =-0.702，P < 0.001）的变化显著相关。结论：手术后视网膜分叉与中央凹的距离呈不对称性扩大，且与形态学改变显著相关。这些结果表明，水平黄斑收缩与垂直视网膜收缩的眼睛与ERM。
The purpose of this cross-sectional retrospective study was to determine the relationship between the retinal displacements and the retinal thickness in eyes with epiretinal membrane (ERM) after vitrectomy with internal limiting membrane (ILM) peeling. To accomplish this, we measured the retinal thickness using optical coherence tomography (OCT) and the retinal displacement using OCT angiography to obtain 3 mm x 3 mm en face images before, and 2, 4, and 8 weeks following the surgery from 20 eyes of 20 patients. The distance between the retinal vessel bifurcations and the fovea was significantly displaced centrifugally and asymmetrically in the 4 quadrants postoperatively (P < 0.001). The foveal avascular zone (FAZ) was significantly enlarged, and the central foveal thickness (CFT) and the inner nuclear layer (INL) thickness were significantly thinner postoperatively. The displacements were significantly correlated with the changes in the FAZ area (r = 0.717, P < 0.001), the CFT (r = - 0.702, P < 0.001), and the INL thickness (r = - 0.702, P < 0.001). In conclusion, the distance between the retinal bifurcations and the fovea was asymmetrically expanded after the surgery and was significantly correlated with the morphological changes. These results indicate that a horizontal macular contraction is correlated with vertical retinal contraction in the eyes with an ERM.