Three-Dimensional Multiphase Time-Resolved Low-Dose Contrast-Enhanced Magnetic Resonance Angiography Using TWIST on a 32-Channel Coil at 3 T: A Quantitative and Qualitative Comparison of a Conventional Gadolinium Chelate With a High-Relaxivity Agent
Three-Dimensional Multiphase Time-Resolved Low-Dose Contrast-Enhanced Magnetic Resonance Angiography Using TWIST on a 32-Channel Coil at 3 T: A Quantitative and Qualitative Comparison of a Conventional Gadolinium Chelate With a High-Relaxivity Agent
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在 3 T 的 32 通道线圈上使用 TWIST 进行三维多相时间分辨低剂量对比增强磁共振血管造影：传统钆螯合物与高弛豫剂的定量和定性比较
DOI：
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发表时间：
2010
影响因子：
1.3
通讯作者：
M. Essig
中科院分区：
文献类型：
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作者：
F. Giesel;V. Runge;M. Kirchin;A. Mehndiratta;L. Gerigk;Body Corell;Carl von Gall;H. Kauczor;M. Essig
目的：评估低剂量对比增强磁共振血管造影（CE-MRA）在高时间和空间分辨率下对腹部血管结构的成像。材料和方法：使用原型 32 通道线圈对 8 只雄性新西兰白兔进行 3 T 增强磁共振血管造影（TWIST [时间分辨血管造影与交错随机轨迹]）。钆特醇（Gd-HP-DO3A，ProHance；Bracco Imaging SpA，米兰，意大利）和高弛豫剂钆贝酸二葡胺（Gd-BOPTA，MultiHance；Bracco Imaging SpA）的剂量均为 0.04 mmol/kg 体重，用于个体间比较。对主动脉和邻近组织中的感兴趣区域进行对比噪声比（CNR）的定量分析。主动脉、髂外动脉和腔静脉的图像质量由 2 位独立的盲读员将图像质量从优秀 (1) 到较差 (3) 进行分类。结果：使用钆贝酸二葡胺获得了显着（P < 0.001）更高的 CNR。 CNR 的改善可以更好地描绘髂外动脉。定性评级显示，钆贝酯二葡胺的图像质量非常好，而钆特醇的图像质量则足够。结论：使用高弛豫剂钆贝酸二葡胺可以改善使用 32 通道体积线圈在 3 T 下进行的时间分辨 CE-MRA，从而提高血管增强的质量和数量。缩写：TWIST - 具有交错随机轨迹的时间分辨血管造影，tr-CE-MRA - 时间分辨对比增强 MR 血管造影
Purpose: To evaluate low-dose contrast-enhanced magnetic resonance angiography (CE-MRA) at high temporal and spatial resolution for imaging of abdominal vascular structures. Materials and Methods: Contrast-enhanced magnetic resonance angiography (TWIST [time-resolved angiography with interleaved stochastic trajectories]) was performed in 8 male New Zealand white rabbits at 3 T using a prototype 32-channel coil. Gadoteridol (Gd-HP-DO3A, ProHance; Bracco Imaging SpA, Milan, Italy) and the high-relaxivity agent gadobenate dimeglumine (Gd-BOPTA, MultiHance; Bracco Imaging SpA), each at a dose of 0.04 mmol/kg body weight, were used in an intraindividual comparison. Quantitative analysis of contrast-to-noise ratio (CNR) was performed in regions of interest placed in the aorta and the adjacent tissues. The image quality in the aorta, external iliac artery, and vena cava was categorized by 2 independent blinded readers from excellent (1) to poor (3). Results: A significantly (P < 0.001) higher CNR was obtained with gadobenate dimeglumine. The improved CNR led to a better delineation of the external iliac arteries. Qualitative rating showed the image quality to be excellent for gadobenate dimeglumine and adequate for gadoteridol. Conclusions: Time-resolved CE-MRA performed at 3 T with a 32-channel volume coil can be improved using the high-relaxivity agent gadobenate dimeglumine, which increases quality and quantity of vessel enhancement.Abbreviations: TWIST - time-resolved angiography with interleaved stochastic trajectories, tr-CE-MRA - time-resolved contrast-enhanced MR angiography
影响因子：
19.7
作者：
Wilman, AH;Riederer, SJ;Ehman, RL
通讯作者：
Ehman, RL