Cathartic effect of the leaf extract of Vernonia amygdalina
Cathartic effect of the leaf extract of Vernonia amygdalina
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DOI：
10.1016/s0367-326x(99)00017-9
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发表时间：
1999-04-01
期刊：
影响因子：
3.4
通讯作者：
Olajide, OA
中科院分区：
文献类型：
--
作者：
Awe, SO;Makinde, JM;Olajide, OA
对苦杏仁叶甲醇提取物的通便效果进行了评价。在炭粉试验中，该提取物对小鼠肠道蠕动有显著的促进作用。在给药后，排便频率和粪便明显增加，提取物也促进了胃排空。对离体大鼠眼底条的初步研究显示出阿托品阻断的收缩作用。(C) 1999 Elsevier Science B.V.版权所有
A methanol extract of Vernonia amygdalina leaves was evaluated for cathartic effect. The extract exhibited a significant promotion of intestinal motility on charcoal meal test in mice. Frequency of defecation and of faeces were markedly increased following administration of the extract which also promoted gastric emptying in rats. Preliminary studies on the isolated rat fundus strip showed a contractile effect, which was blocked by atropine. (C) 1999 Elsevier Science B.V. All rights reserved.