Carcinoma Cuniculatum Arising in the Tongue
Carcinoma Cuniculatum Arising in the Tongue
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DOI：
10.1007/s12105-011-0270-2
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发表时间：
2012-03-01
影响因子：
2.1
通讯作者：
Jay, Amrita
中科院分区：
文献类型：
--
作者：
Thavaraj, Selvam;Cobb, Alistair;Jay, Amrita
楔状癌（CC）是鳞状细胞癌（SCC）的一种罕见的，独特的临床病理学变体，其组织学特征是具有角蛋白核心和角蛋白填充的隐窝的复层鳞状上皮的深，宽和复杂增殖的特征性浸润模式。在此，我们提出一个病例报告CC的口腔舌头，并讨论其诊断，管理和结果，以及简要回顾世界文献。据我们所知，这是第一个记录的情况下CC的舌头被报道在英语文献。我们提请注意其临床病理特征，并强调，认识到这种实体作为一个独特的变异SCC有利于其正确的管理。
Carcinoma cuniculatum (CC) is a rare, distinct clinico-pathological variant of squamous cell carcinoma (SCC) that is defined histologically by the characteristic infiltrative pattern of a deep, broad, and complex proliferation of stratified squamous epithelium with keratin cores and keratin-filled crypts. Herein, we present a case report of CC of the oral tongue and discuss its diagnosis, management, and outcome, as well as briefly review the world literature. To our knowledge, this is the first documented case of CC of the tongue to be reported in the English literature. We draw attention to its clinico-pathological features and highlight that awareness of this entity as a distinct variant of SCC facilitates its correct management.