Equity considerations in outcome measures of the HIV pre-exposure prophylaxis care continuum in high-income countries: a systematic review protocol.

Equity considerations in outcome measures of the HIV pre-exposure prophylaxis care continuum in high-income countries: a systematic review protocol.
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DOI:
10.1136/bmjopen-2020-040701
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发表时间:
2021-02-04
期刊:
影响因子:
2.9
通讯作者:
McDonagh LK
McDonagh LK
中科院分区:
医学3区
文献类型:
--
作者:
Cabecinha M;Solomon D;Rait G;Saunders J;Mohammed H;McDonagh LK

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HIV暴露前预防(PrEP)是减少HIV感染的有效干预措施。近年来,预防措施的提供有所增加,但是,目前尚不清楚是否在所有风险群体,特别是经历严重卫生不平等的群体中公平地实施了预防措施。已经提出了一个PrEP护理连续体(PCC)来评估PrEP实施规划的成功,但PCC目前在多大程度上考虑了卫生公平特征,尚未得到描述。这项拟议的系统综述的目标是:(i)确定和整理PCC主要阶段(意识、可接受性、吸收、遵守和保留)的结果测量定义,(ii)描述PCC的结果定义如何考虑公平特征,以及(iii)描述捕获公平特征的数据源。2012年1月1日至2020年3月3日期间发表的定量研究将被纳入。将检索五个数据库(MEDLINE、PubMed、Embase、护理和相关健康文献累积索引、应用社会科学索引和摘要),以确定包含PCC五个主要阶段中至少一个结果测量定义的英文出版物。将使用定量研究的有效公共卫生实践项目质量评估工具来评估偏倚风险。将提取有关结果衡量标准定义和公平特征的数据。结果将以叙述性综合形式呈现,所有发现将按照系统评价和荟萃分析指南的首选报告项目进行报告。不需要伦理批准。完成后,研究结果将通过提交给同行评审期刊的方式进行传播。审查结果将与卫生保健专业人员、决策者和专员有关,告知如何最好地评估预防措施实施规划,并为脆弱和处境不利人群的新实施战略提供信息。CRD42020169779。
HIV pre-exposure prophylaxis (PrEP) is an effective intervention to reduce acquisition of HIV. PrEP provision has increased in recent years, however, it is not known whether PrEP implementation has been equitably implemented across all risk groups, particularly groups experiencing high levels of health inequity. A PrEP care continuum (PCC) has been proposed to evaluate the success of PrEP implementation programmes, but the extent to which health equity characteristics are currently taken into account in the PCC has not been described. The objectives of this proposed systematic review are to (i) identify and collate outcome measure definitions for the main stages of the PCC (awareness, acceptability, uptake, adherence and retention), (ii) describe how equity characteristics are considered in outcome definitions of the PCC and (iii) describe data sources for capturing equity characteristics. Quantitative studies published between 1 January 2012 and 3 March 2020 will be included. Five databases (MEDLINE, PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, Applied Social Sciences Index and Abstracts) will be searched to identify English language publications that include an outcome measure definition of at least one of the five main stages of the PCC. Risk of bias will be assessed using the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies. Data on outcome measure definitions and equity characteristics will be extracted. Results will be presented in a narrative synthesis and all findings will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Ethical approval is not required. The results will be disseminated via submission for publication to a peer-reviewed journal when complete. The review findings will have relevance to healthcare professionals, policymakers and commissioners in informing how to best evaluate PrEP implementation programmes and inform new implementation strategies for vulnerable and less advantaged populations. CRD42020169779.
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