Photoprotection in the Era of Nanotechnology
Photoprotection in the Era of Nanotechnology
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DOI：
10.1016/j.sder.2011.07.006
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发表时间：
2011-12-01
影响因子：
--
通讯作者：
Tooley, Ian R.
中科院分区：
文献类型：
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作者：
Wang, Steven Q.;Tooley, Ian R.
与老一代的无机防晒霜相比，基于纳米二氧化钛（TiO2）和氧化锌（ZnO）的商用防晒霜提供了卓越的紫外线防护，并减少了皮肤的美白。本文综述了纳米二氧化钛和氧化锌在防晒霜中的历史应用，以及构成这些无机氧化物的主要颗粒、聚集体和团聚体与紫外线衰减的关系。此外，我们回顾了最近关于这些材料的安全问题，特别是二氧化钛和氧化锌纳米粒子通过人体皮肤的经皮渗透及其引起光毒性的可能性。中国生物医学工程杂志（英文版）(C) 2011版权所有。
Commercial sunscreen based on nano-sized titanium dioxide (TiO2) and zinc oxide (ZnO) delivers superior UV protection and reduces whitening on skin compared to the older generations of inorganic sunscreens. This review discusses the historical use of nano-sized TiO2 and ZnO in sunscreen and the relationship between UV attenuation and the primary particles, aggregates and agglomerates that make up these inorganic oxides. In addition we reviewed the recent safety concerns surrounding these materials, specifically, percutaneous penetration of TiO2 and ZnO nanoparticles through human skin and their potential to cause phototoxicity. Semin Cutan Med Surg 30:210-213 (C) 2011 Elsevier Inc. All rights reserved.