Factors influencing stroke survivors' quality of life during subacute recovery
Factors influencing stroke survivors' quality of life during subacute recovery
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DOI：
10.1161/01.str.0000170706.13595.4f
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发表时间：
2005-07-01
期刊：
影响因子：
8.3
通讯作者：
Blanton, S
中科院分区：
文献类型：
--
作者：
Nichols-Larsen, DS;Clark, PC;Blanton, S
背景和目的：健康相关生活质量（HRQOL）是卒中后结局的一个重要指标，可能有助于更广泛地描述卒中恢复。本研究探讨了个体和临床特征的关系，以HRQOL中风幸存者与轻度至中度中风在亚急性recovery.Methods -二百二十九名参与者3至9个月后中风被纳入一个国家的多地点临床试验（xtremity约束诱导治疗评价）。使用卒中影响量表（SIS）3.0版评估HRQOL。Wolf运动功能测试记录了偏瘫上肢的功能恢复。多元方差分析和回归模型研究了SIS domains.Results的人口统计学和临床变量的影响，年龄，性别，教育水平，中风类型，一致性（瘫痪臂=优势手），上肢运动功能（Wolf运动功能测试），并合并症与SIS域。身体领域的POST-HRQOL与年龄、非白人种族、更多的合并症和上肢功能降低相关。中风幸存者有更多的合并症报告较差的HRQOL在该地区的记忆和思维，和那些缺血性中风和一致性报告较差的communication.Conclusions -虽然结果可能不会推广到功能较低的中风幸存者，个人特点的轻度至中度中风的人可能是重要的考虑在制定全面的，有针对性的干预措施，旨在最大限度地恢复和改善HRQOL。
Background and Purpose - Health-related quality of life (HRQOL) is an important index of outcome after stroke and may facilitate a broader description of stroke recovery. This study examined the relationship of individual and clinical characteristics to HRQOL in stroke survivors with mild to moderate stroke during subacute recovery.Methods - Two hundred twenty-nine participants 3 to 9 months poststroke were enrolled in a national multisite clinical trial ( xtremity Constraint-Induced Therapy Evaluation). HRQOL was assessed using the Stroke Impact Scale (SIS), Version 3.0. The Wolf Motor Function Test documented functional recovery of the hemiplegic upper extremity. Multiple analysis of variance and regression models examined the influence of demographic and clinical variables across SIS domains.Results - Age, gender, education level, stroke type, concordance (paretic arm = dominant hand), upper extremity motor function ( Wolf Motor Function Test), and comorbidities were associated across SIS domains. Poorer HRQOL in the physical domain was associated with age, nonwhite race, more comorbidities, and reduced upper-extremity function. Stroke survivors with more comorbidities reported poorer HRQOL in the area of memory and thinking, and those with an ischemic stroke and concordance reported poorer communication.Conclusions - Although results may not generalize to lower functioning stroke survivors, individual characteristics of persons with mild to moderate stroke may be important to consider in developing comprehensive, targeted interventions designed to maximize recovery and improve HRQOL.