Palladium-Catalyzed Intramolecular Trapping of the Blaise Reaction Intermediate for Tandem One-Pot Synthesis of Indole Derivatives

Palladium-Catalyzed Intramolecular Trapping of the Blaise Reaction Intermediate for Tandem One-Pot Synthesis of Indole Derivatives
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DOI:
10.1021/ol200045q
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发表时间:
2011-03-18
期刊:
影响因子:
5.2
通讯作者:
Lee, Sang-gi
Lee, Sang-gi
中科院分区:
化学1区
文献类型:
--
作者:
Kim, Ju Hyun;Lee, Sang-gi

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钯催化的Blaise反应中间体分子内n -芳基化和n -烷基化/ n -芳基化陷阱可能是一种从腈基串联一锅法构建吲哚基团的新途径。
Palladium-catalyzed intramolecular N-arylative and N-alkylative/N-arylative trappings of the Blaise reaction intermediates could be a new route to construct the indole moiety in a tandem one-pot manner from nitriles.