Effectiveness of combined use of imprint cytological and histological examination in CT-guided tissue-core biopsy
Effectiveness of combined use of imprint cytological and histological examination in CT-guided tissue-core biopsy
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DOI：
10.1007/s00330-014-3104-2
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发表时间：
2014-05-01
影响因子：
5.9
通讯作者：
Awai, Kazuo
中科院分区：
文献类型：
--
作者：
Yamagami, Takuji;Yoshimatsu, Rika;Awai, Kazuo
本研究评估了印记细胞学和组织学相结合在实时计算机断层扫描（CT）透视引导下经皮组织核心活检的效果。2009年10月至2013年6月，我机构进行了156例经皮穿刺活检。组织核心活检获得的样本在现场进行接触印记细胞学检查后，常规进行印记细胞学和组织学检查，以评估样本是否足以进行细胞学和病理学检查。最终诊断由独立的手术病理学、独立的培养结果或临床随访证实。细胞学和组织学联合检查的充足标本和精确诊断率分别为100%（156/156）和96.2%（150/156），细胞学检查94.4%（152/156）和83.3%（130/156）和组织学检查准确诊断率99.3% (155/156) 和 92.3% (144/156)。胸部病变联合检查准确率达94.7%（89/94），肌肉骨骼病变达97.6%（40/41），腹部、盆腔及腹膜后病变达100%（21/21）。在所有 104 个经 CT 引导活检诊断为恶性的病灶中，在 52 个诊断为良性的病灶中，通过联合检查可以证明特定的细胞类型。在现场接触印记细胞学评估后进行的印记细胞学和组织学联合提高了 CT 透视引导活检的诊断能力。a 欧元 CT 引导针吸活检是一种成熟的诊断方法 现场触摸印记细胞学评估有助于提高CT引导活检的质量。a欧元细胞学检查对恶性淋巴瘤的特异诊断率较低。a欧元肌肉骨骼区域良性病变的特异诊断率较低。
This study evaluated the efficacy of the combination of imprint cytology and histology in tissue-core percutaneous biopsy under real-time computed tomography (CT) fluoroscopic guidance.Between October 2009 and June 2013, 156 percutaneous needle biopsies were performed in our institution. Those obtained by tissue-core biopsy underwent both imprint cytological and histological examinations routinely after touch imprint cytology was performed on site to evaluate the samples' sufficiency for cytological and pathological examination. Final diagnosis was confirmed by independent surgical pathology, independent culture results or clinical follow-up.Rates of adequate specimens and precise diagnosis, by combined cytological and histological examination were 100 % (156/156) and 96.2 % (150/156), by cytology 94.4 % (152/156) and 83.3 % (130/156) and by histology 99.3 % (155/156) and 92.3 % (144/156). Precise diagnosis was achieved by combined examinations in 94.7 % (89/94) of thoracic lesions, 97.6 % (40/41) of musculoskeletal lesions, and 100 % (21/21) of abdominal, pelvic and retroperitoneal lesions. In all 104 lesions diagnosed as malignant by CT-guided biopsy and in 30 of 52 diagnosed as benign, specific cell types could be proved by combined examinations.Combined imprint cytology and histology performed after on-site touch imprint cytological evaluation improved the diagnostic ability of CT fluoroscopically guided biopsy.aEuro cent CT-guided needle biopsy is a well-established diagnostic technique.aEuro cent Touch imprint cytological evaluation on site is helpful in improving quality of CT-guided biopsy.aEuro cent The rate of diagnosing malignant lymphoma specifically with cytological examination is relatively low.aEuro cent The rate of specific diagnosis of benign lesion in musculoskeletal regions is low.