Development of electrochemical paper‐based glucose sensor using cellulose‐4‐aminophenylboronic acid‐modified screen‐printed carbon electrode
Development of electrochemical paper‐based glucose sensor using cellulose‐4‐aminophenylboronic acid‐modified screen‐printed carbon electrode
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DOI：
10.1002/elan.201500406
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发表时间：
2016-03
期刊：
影响因子：
3
通讯作者：
T. Rungsawang;Eakkasit Punrat;Jaclyn A. Adkins;C. Henry;O. Chailapakul
中科院分区：
文献类型：
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作者：
T. Rungsawang;Eakkasit Punrat;Jaclyn A. Adkins;C. Henry;O. Chailapakul
目前的工作描述了通过将葡萄糖氧化酶固定到丝网印刷碳电极（SPCE）上来制造纸基分析装置（μPAD），用于电化学葡萄糖检测。通过使用自制碳墨与醋酸纤维素混合制备的 SPCE，提高了对葡萄糖的敏感性。此外，4-氨基苯基硼酸 (4-APBA) 用作氧化还原介体，可降低检测潜力，从而提高选择性。在优化条件下，检测限为0.86 mM。 The proposed device was applied in real samples.该μPAD具有样品消耗少、分析方法快速、设备成本低等优点。
The present work describes the fabrication of paper-based analytical devices (μPADs) by immobilization of glucose oxidase onto the screen printed carbon electrodes (SPCEs) for the electrochemical glucose detection. The sensitivity towards glucose was improved by using a SPCE prepared from homemade carbon ink mixed with cellulose acetate. In addition, 4-aminophenylboronic acid (4-APBA) was used as a redox mediator giving a lower detection potential for improvement selectivity. Under optimized condition, the detection limit was 0.86 mM. The proposed device was applied in real samples. This μPAD has many advantages including low sample consumption, rapid analysis method, and low device cost.