Pulse sequence for multislice T1ρ-weighted MRI

Pulse sequence for multislice T1ρ-weighted MRI
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DOI:
10.1002/mrm.10705
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发表时间:
2004-02-01
影响因子:
3.3
通讯作者:
Reddy, R
Reddy, R
中科院分区:
医学3区
文献类型:
--
作者:
Wheaton, AJ;Borthakur, A;Reddy, R

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二维多层自旋锁(MS-SL)磁共振脉冲序列提出了快速体积t -1p加权成像。将图像质量与单片(SS) SL序列收集的t -1p加权数据和标准MS自旋回波(SE)序列收集的t -2加权数据进行比较。实验测量了非选择性SL脉冲对纵向磁化饱和的影响,并建立了T-2p衰变的理论模型。饱和度数据用于校正图像数据作为SL脉冲持续时间的函数,以定量测量TIP。使用饱和度校正的MS-SL数据测量的T-1p与使用SS-SL序列测量的T-1p几乎相同。MS-SL序列产生整个样本量的定量T-1p图谱,具有se序列所赋予的高信噪比优势。(C) 2004 Wiley-Liss, Inc。
A 2D multislice spin-lock (MS-SL) MR pulse sequence is presented for rapid volumetric T-1p-weighted imaging. Image quality is compared with T-1p-weighted data collected using a single-slice (SS) SL sequence and T-2-weighted data from a standard MS spin-echo (SE) sequence. Saturation of longitudinal magnetization by the application of nonselective SL pulses is experimentally measured and theoretically modeled as T-2p decay. The saturation data is used to correct the image data as a function of the SL pulse duration to make quantitative measurements of TIP. Measurements of T-1p using the saturation-corrected MS-SL data are nearly identical to those measured using an SS-SL sequence. The MS-SL sequence produces quantitative T-1p maps of an entire sample volume with the high-SNR advantages conferred by SE-based sequences. (C) 2004 Wiley-Liss, Inc.