Age- and gender-related collagen distribution in human vocal folds
Age- and gender-related collagen distribution in human vocal folds
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DOI：
10.1177/000348940010901004
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发表时间：
2000-10-01
影响因子：
1.4
通讯作者：
Butler, JE
中科院分区：
文献类型：
--
作者：
Hammond, TH;Gray, SD;Butler, JE
人类声带固有层的组成已被证明会影响发声表现。胶原蛋白在固有层的生物力学效应中发挥着重要作用。具体来说，它为快速振荡的折叠提供拉伸强度。我们从一位州法医那里获得了 38 份来自婴儿、成人和老年人年龄组的男性和女性的喉部样本。我们使用苦味酸染色剂对声带进行胶原蛋白染色，并使用图像分析系统对其进行研究。测量固有层内从浅层到深层（从上皮到声带肌）的胶原蛋白分布。数据显示，从婴儿到成人阶段，胶原蛋白含量有所增加。婴儿皱襞中的胶原蛋白含量约为所有成人和老年患者的 51%（p
The composition of the lamina propria in human vocal folds has been shown to affect vocal performance. Collagen plays a significant role in the biomechanical effects of the lamina propria. Specifically, it lends tensile strength to the rapidly oscillating fold. We obtained from a state medical examiner 38 larynges from men and women in infant, adult, and geriatric age groups. We stained the vocal folds for collagen using a picric acid stain and studied them using an image analysis system. Distributions of collagen were measured from the superficial to deep layers (from epithelium to vocalis muscle) within the lamina propria. The data showed an increase in collagen content from infant to adult stages. Infant folds had about 51% of the collagen found in all adults and in geriatric patients (p