An Epidemiological and Etiological Analysis of 5026 Peripheral Nerve Lesions from a European Level I Trauma Center.

An Epidemiological and Etiological Analysis of 5026 Peripheral Nerve Lesions from a European Level I Trauma Center.
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DOI:
10.3390/jpm12101673
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发表时间:
2022-10-08
影响因子:
--
通讯作者:
Harhaus L
Harhaus L
中科院分区:
医学4区
文献类型:
--
作者:
Aman M;Zimmermann KS;Thielen M;Thomas B;Daeschler S;Boecker AH;Stolle A;Bigdeli AK;Kneser U;Harhaus L

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背景:周围神经病变与衰弱的长期后果有关。尽管流行病学和病因学数据对循证临床决策至关重要,但却很少。因此,我们的目的是在最大的队列之一中全面分析周围神经病变的流行病学和病因学因素。方法:我们筛选了2012年1月至2020年7月在我们的一级创伤中心接受神经病变治疗的110,667例患者。随后,分析了人口统计学、病因学、伴随损伤和病变特征。结果:共治疗5026例与工作无关的神经损伤患者,主要为年轻男性。近端损伤多伴有骨折,而远端损伤多伴有血管或肌腱损伤。主要原因为54.6%的撕裂伤。急性外伤性神经损伤24 h内治疗率为55.9%。结论:考虑到受影响患者的年龄,在专业中心进行早期诊断和治疗可能有助于他们早日重返工作岗位,并改善长期功能预后。数据显示了对神经损伤特别关注的重要性,这可能被伴随的大损伤所掩盖。关于选定亚组的病变特征和伴随情况的新发现可以支持治疗策略的改变。
Background: Peripheral nerve lesions are associated with debilitating long-term consequences. Albeit being essential for evidence-based clinical decision making, epidemiological and etiological data are scarce. We therefore aimed to comprehensively analyze epidemiological and etiological factors of peripheral nerve lesions in one of the largest cohorts. Methods: We screened a total of 110,667 patients treated at our level I trauma center between January 2012 and July 2020 for nerve lesions. Subsequently, demographics, etiologies, concomitant injuries, and lesion characteristics were analyzed. Results: A total of 5026 patients, predominantly young males suffering from non-work-related nerve injuries, were treated. Proximal levels of injury were more likely to be accompanied by fractures, whereas more distal injuries with concomitant vessel or tendon injury. Main causes were 54.6% lacerations. Acute traumatic nerve injury was treated within 24 h in 55.9% of cases. Conclusions: Given the young age of affected patients, early diagnosis and treatment in specialized centers may facilitate their early return to work and improve long-term functional outcomes. The data show the importance of a special attention on nerve injuries, which may be masked by large accompanying injuries. New findings on lesion characteristics of selected subgroups and accompanying circumstances can support a change in treatment strategies.
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