MutationFinder: a high-performance system for extracting point mutation mentions from text

MutationFinder: a high-performance system for extracting point mutation mentions from text
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DOI:
10.1093/bioinformatics/btm235
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发表时间:
2007-07-15
期刊:
影响因子:
5.8
通讯作者:
Hunter, Lawrence
Hunter, Lawrence
中科院分区:
生物学3区
文献类型:
--
作者:
Caporaso, J. Gregory;Baumgartner, William A., Jr.;Hunter, Lawrence

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摘要:点突变的讨论在生物医学文献中无处不在,手动编辑关于特定基因或蛋白质突变的数据库或文献是乏味的。我们提出了一个开源的,基于规则的系统,MutationFincler,从文本中提取点突变提到。在盲测数据上,它实现了近乎完美的精确度,并在基线上显著提高了召回率。
ummary: Discussion of point mutations is ubiquitous in biomedical literature, and manually compiling databases or literature on mutations in specific genes or proteins is tedious. We present an open-source, rule-based system, MutationFincler, for extracting point mutation mentions from text. On blind test data, it achieves nearly perfect precision and a markedly improved recall over a baseline.