Three new sesquiterpenoids from cultures of the basidiomycete Conocybe siliginea
Three new sesquiterpenoids from cultures of the basidiomycete Conocybe siliginea
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DOI：
10.1080/10286020.2014.939072
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发表时间：
2015-01
影响因子：
1.7
通讯作者：
Xiao-Yan Yang;Zheng-Hui Li;Zejun Dong;Tao Feng;Jikai Liu
中科院分区：
文献类型：
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作者：
Xiao-Yan Yang;Zheng-Hui Li;Zejun Dong;Tao Feng;Jikai Liu
3个新倍半萜类化合物(1-3)和4个已知化合物(4-7)是从硅藻孢子菌的培养物中分离得到的。用波谱方法对新化合物的结构进行了鉴定。将已知化合物的光谱数据与文献报道的数据进行比较，确定了化合物的结构。所有新化合物对五种人类癌细胞株的细胞毒性进行了评估，但没有一种化合物具有显著的活性(IC50>；40μM)。
Three new sesquiterpenoids (1–3), along with four known compounds (4–7), were isolated from cultures of the fungus Conocybe siliginea. The structures of new compounds were elucidated using spectroscopic methods. The known compounds were identified by comparing their spectroscopic data with those reported in the literature. All new compounds were evaluated for cytotoxicity against five human cancer cell lines, but none of them possesses significant activity (IC50>40μM).