Effects of Response to 2014-2015 Ebola Outbreak on Deaths from Malaria, HIV/AIDS, and Tuberculosis, West Africa.
Effects of Response to 2014-2015 Ebola Outbreak on Deaths from Malaria, HIV/AIDS, and Tuberculosis, West Africa.
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DOI：
10.3201/eid2203.150977
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发表时间：
2016-03
影响因子：
11.8
通讯作者：
Galvani AP
中科院分区：
文献类型：
--
作者：
Parpia AS;Ndeffo-Mbah ML;Wenzel NS;Galvani AP
疫情期间获得医疗保健的机会减少，大大增加了其他疾病的死亡率。对2014-2015年西非埃博拉疫情的应对措施使几内亚、利比里亚和塞拉利昂的医疗系统不堪重负，减少了该地区流行的主要疾病（疟疾、艾滋病毒/艾滋病和结核病）的诊断和治疗卫生服务。为了估计埃博拉疫情对这些疾病风险人群的影响，我们开发了疾病传播和感染进展的计算模型。我们估计，在埃博拉疫情爆发期间，获得医疗服务的机会减少50%，导致疟疾、艾滋病毒/艾滋病和结核病死亡率增加，几内亚死亡人数增加6，269人（2，564 - 12，407）;利比里亚增加1，535人（522- 2，8780）;塞拉利昂增加2，819人（844- 4，844）。2014-2015年埃博拉疫情在这些国家造成了灾难性的影响，其增加其他疾病死亡率的间接影响也很大。
Reduced access to healthcare during the outbreak substantially increased mortality rates from other diseases. Response to the 2014–2015 Ebola outbreak in West Africa overwhelmed the healthcare systems of Guinea, Liberia, and Sierra Leone, reducing access to health services for diagnosis and treatment for the major diseases that are endemic to the region: malaria, HIV/AIDS, and tuberculosis. To estimate the repercussions of the Ebola outbreak on the populations at risk for these diseases, we developed computational models for disease transmission and infection progression. We estimated that a 50% reduction in access to healthcare services during the Ebola outbreak exacerbated malaria, HIV/AIDS, and tuberculosis mortality rates by additional death counts of 6,269 (2,564–12,407) in Guinea; 1,535 (522–2,8780) in Liberia; and 2,819 (844–4,844) in Sierra Leone. The 2014–2015 Ebola outbreak was catastrophic in these countries, and its indirect impact of increasing the mortality rates of other diseases was also substantial.