Intramedullary spinal cord metastasis from pancreatic neuroendocrine tumor

Intramedullary spinal cord metastasis from pancreatic neuroendocrine tumor
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DOI:
10.3748/wjg.v20.i38.14063
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发表时间:
2014-10-14
影响因子:
4.3
通讯作者:
Han, Sang Hoon
Han, Sang Hoon
中科院分区:
医学2区
文献类型:
--
作者:
Kim, Jung Ho;Hyun, Chang Lim;Han, Sang Hoon

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脊髓髓内转移(ISCM)非常罕见,其最佳治疗方法仍存在争议。胰腺神经内分泌肿瘤(pNET)是一种罕见的肿瘤,通常表现为肝转移。肿瘤进展导致的肝衰竭是 pNET 病例死亡的主要原因。迄今为止,还没有报告描述 pNET 的 ISCM 病例。尽管实体瘤的脊髓转移并不常见,但它是一种可能导致潜在不可逆转的神经功能丧失的危急病症。在这里,我们报告一名 45 岁男性的病例,他出现腿部无力和排尿困难,并被 pNET 发现患有 ISCM。手术治疗防止了神经系统进一步恶化。这是 pNET 的第一份 ISCM 病例报告。 (C) 2014 百事登出版集团有限公司版权所有。
Intramedullary spinal cord metastasis (ISCM) is very rare and its optimal treatment remains controversial. Pancreatic neuroendocrine tumor (pNET) is a rare tumor that usually presents with hepatic metastasis. Hepatic failure due to tumor progression is the major cause of death in cases of pNET. To date, no report has described a case of ISCM from pNET. Although spinal cord metastasis of a solid tumor is uncommon, it is a critical condition that can cause a potentially irreversible loss of neurologic function. Here, we report the case of a 45-year-old man who presented with leg weakness and voiding difficulty, and was found to have ISCM from pNET. Surgical treatment prevented further neurological deterioration. This is the first case report of ISCM from pNET. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.