The ancestry of Brazilian mtDNA lineages
The ancestry of Brazilian mtDNA lineages
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DOI：
10.1086/303004
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发表时间：
2000-08-01
影响因子：
9.8
通讯作者：
Prado, VF
中科院分区：
文献类型：
--
作者：
Alves-Silva, J;Santos, MD;Prado, VF
我们分析了247个巴西mtDNA的高变段（HVS）-I和选择的限制性片段长度多态性位点，以评估他们在不同大陆的祖先。总样本显示几乎等量的美洲原住民，非洲和欧洲母系遗传的贡献，但在巴西的区域差异。现代巴西人的线粒体DNA库清楚地反映了早期葡萄牙殖民过程（包括定向交配）的印记，以及最近世纪的移民浪潮（来自欧洲）。从东南部地区的99个mtDNA的子集包括几乎所有的mtDNA单倍型组中观察到的总的巴西样本，这个区域的子集，HVS-II进行了分析，特别是提供了一些新的细节非洲的mtDNA单倍型。
We have analyzed 247 Brazilian mtDNAs for hypervariable segment (HVS)-I and selected restriction fragment-length-polymorphism sites, to assess their ancestry in different continents. The total sample showed nearly equal amounts of Native American, African, and European matrilineal genetic contribution but with regional differences within Brazil. The mtDNA pool of present-day Brazilians clearly reflects the imprints of the early portuguese colonization process (involving directional mating), as well as the recent immigrant waves (from Europe) of the last century. The subset of 99 mtDNAs from the southeastern region encompasses nearly all mtDNA haplogroups observed in the total Brazilian sample; for this regional subset, HVS-II was analyzed, providing, in particular, some novel details of the African mtDNA phylogeny.