Meta-analysis of the relationship between breaks in sedentary behavior and cardiometabolic health
Meta-analysis of the relationship between breaks in sedentary behavior and cardiometabolic health
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DOI：
10.1002/oby.21180
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发表时间：
2015-09-01
期刊：
影响因子：
6.9
通讯作者：
Stamatakis, Emmanuel
中科院分区：
文献类型：
--
作者：
Chastin, Sebastien F. M.;Egerton, Thorlene;Stamatakis, Emmanuel
久坐行为中的休息的概念已经成为久坐行为对肥胖造成的有害影响的潜在修正剂。现有的研究调查久坐行为与肥胖和心脏代谢健康的成年人之间的关系中断进行了系统的审查和定量合成由this study.MethodsObservational和实验研究，研究久坐行为和肥胖和心脏代谢健康的标志物的频率之间的关系进行了系统的文献检索确定。通过使用实验性试验的逆方差法和观察性研究的休息与肥胖和心脏代谢标志物之间存在关联的贝叶斯后验概率进行荟萃分析。结果如下：九项实验研究的汇总结果表明，至少在光照强度的久坐时间内休息可能对成年人的血糖有积极影响，但对血脂没有影响。目前尚不清楚这种影响是否与总的坐着时间无关。然而，10个确定的观察性研究表明，与休息，这是独立的总久坐不动的时间，但只有肥胖metrics.ConclusionsThe理论，中断的久坐不动的行为与光强度的活动可能有助于控制肥胖和餐后肥胖的证据支持。有必要进一步研究更好的测量久坐行为模式的方法和改进的研究设计，以证实这一初步证据。
ObjectiveThe concept of breaks in sedentary behavior has emerged as a potential modifier of detrimental effects on adiposity caused by sedentary behavior. The existing research investigating the relationship between breaks in sedentary behavior with adiposity and cardiometabolic health in adults was systematically reviewed and quantitatively synthesized by this study.MethodsObservational and experimental studies that examined the relationships between the frequency of interruptions of sedentary behavior and markers of adiposity and cardiometabolic health in adults were identified by a systematic search of the literature. A meta-analysis was conducted by using the inverse variance method for experimental trials and a Bayesian posterior probability of existence of an association between breaks with adiposity and cardiometabolic markers for observational studies. Results: It was revealed by the pooled results from nine experimental studies that breaks in sedentary periods of at least light intensity may have a positive effect on glycemia but not on lipidemia for adults. It is unclear whether this effect is independent of total sitting time. However, the 10 identified observational studies showed an association with breaks, which was independent of total sedentary time, but only for obesity metrics.ConclusionsThe theory that interrupting bouts of sedentary behavior with light-intensity activity might help control adiposity and postprandial glycemia was supported by the evidence. Further investigations with better methods of measuring sedentary behavior patterns and improved study designs are necessary to confirm this preliminary evidence.