The language of histone crosstalk.
The language of histone crosstalk.
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DOI:
10.1016/j.cell.2010.08.011
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发表时间:
2010-09-03
期刊:
影响因子:
64.5
通讯作者:
Shilatifard A
中科院分区:
文献类型:
--
作者:
Lee JS;Smith E;Shilatifard A
It has been suggested that a specific pattern of histone posttranslational modifications and their crosstalk may constitute a code that determines transcriptional outcomes. However, recent studies indicate that histone modifications have context-dependent effects, making their interplay more like a language within the chromatin signaling pathway than a code.
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