Lean Body Mass in the Prediction of Bone Mineral Density in Postmenopausal Women.
Lean Body Mass in the Prediction of Bone Mineral Density in Postmenopausal Women.
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DOI：
10.1089/biores.2018.0025
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发表时间：
2018
影响因子：
--
通讯作者：
Kruger MC
中科院分区：
文献类型：
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作者：
Ilesanmi-Oyelere BL;Coad J;Roy N;Kruger MC
由于身体成分和骨密度(BMD)之间的相互矛盾的结果，我们调查了新西兰绝经后妇女的脂肪质量(FM)、瘦质量(LM)和BMD之间的关系。我们假设增加的Lm意味着更高的BMD。进行了一项横断面研究，考察了身体成分、人体测量、活动能量消耗和骨健康状况之间的关系(使用双能X射线吸收测量仪[DXA])。共127名健康的绝经后妇女，年龄在54岁到81岁之间。FM和Lm均与所有部位的BMD显著相关。然而，对于股骨颈(FN)骨密度(β = 0.497，p <； 0.001)、髋部骨密度(β = 0.495，p <； 0.001)、脊柱骨密度(β = 0.449，p <； 0.001)和全身骨密度(β = 0.406，p <； 0.001)，最强的预测指标是股骨颈(FN)，而不是FM。年龄与FN、髋部骨密度呈负相关。Lm与FN、脊柱、髋部和全身骨密度呈正相关。我们的研究结果表明，有必要增加LM而不是FM，强调了这一年龄段体力活动的重要性。
Owing to conflicting results of the association between body composition and bone mineral density (BMD), we investigated the relationship between fat mass (FM), lean mass (LM), and BMD in New Zealand postmenopausal women. We hypothesized that increased LM will indicate a higher BMD. A cross-sectional study was performed examining the associations between body composition, anthropometric measures, activity energy expenditure, and bone health status (using dual-energy X-ray absorptiometry [DXA]). A total of 127 healthy postmenopausal women aged between 54 and 81 years. Both FM and LM were significantly associated with BMD at all sites. However, LM, not FM, was the strongest predictor of femoral neck (FN) BMD (β = 0.497, p < 0.001), hip BMD (β = 0.495, p < 0.001), spine BMD (β = 0.449, p < 0.001), and whole body BMD (β = 0.406, p < 0.001). Age was negatively associated with FN and hip BMD. LM was positively associated with FN, spine, hip, and whole body BMD. Our findings suggest the need to increase LM rather than FM highlighting the importance of physical activity for this age group.