Morgan's legacy: fruit flies and the functional annotation of conserved genes.

Morgan's legacy: fruit flies and the functional annotation of conserved genes.
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DOI:
10.1016/j.cell.2015.09.009
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发表时间:
2015-09-24
期刊:
影响因子:
64.5
通讯作者:
Yamamoto S
Yamamoto S
中科院分区:
生物学1区
文献类型:
--
作者:
Bellen HJ;Yamamoto S

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1915年,四位著名的果蝇遗传学家发表了《孟德尔遗传机制》。他们发现基因在染色体上形成连锁群,以孟德尔方式遗传,并奠定了促进果蝇作为模式生物的遗传基础。苍蝇继续提供巨大的机会,包括在功能基因组学领域的研究。
In 1915, “The Mechanism of Mendelian Heredity” was published by four prominent Drosophila geneticists. They discovered that genes form linkage groups on chromosomes inherited in a Mendelian fashion and laid the genetic foundation that promoted Drosophila as a model organism. Flies continue to offer great opportunities, including studies in the field of functional genomics.