PULMONARY EDEMA AS A CONSEQUENCE OF HYPOTHALAMIC LESIONS IN RATS
PULMONARY EDEMA AS A CONSEQUENCE OF HYPOTHALAMIC LESIONS IN RATS
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DOI：
10.1126/science.141.3584.930
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发表时间：
1963-01-01
期刊：
影响因子：
56.9
通讯作者：
REYNOLDS, RW
中科院分区：
文献类型：
--
作者：
REYNOLDS, RW
采用射频热凝或直流电解法观察大鼠下丘脑病变放置后肺水肿的发生率。在有电解损伤的动物中，31%死于肺水肿，另外20%有明显的症状。中度短暂性症状只出现在3.7%的射频损伤动物中，并且在这一组中没有可归因于该综合征的死亡。这些结果表明，这种综合征是电损伤过程的刺激后果，而不是“释放”现象。
Rats were observed for the incidence of pulmonary edema after the placement of hypothalamic lesions by radio frequency thermocoagulation or d-c electrolysis. In the animals with electrolytic lesions, 31 percent died with pulmonary edema and marked signs were observed in another 20 percent. Moderate transient signs appeared in only 3.7 percent of the animals with radio-frequency lesions, and there were no deaths attributable to this syndrome in this group. These results suggest that this syndrome is an irritative consequence of the electrolytic lesion process rather than a "release" phenomenon.