General health and knee function outcomes from 7 days to 12 weeks after spinal anesthesia and multimodal analgesia for anterior cruciate ligament reconstruction.
General health and knee function outcomes from 7 days to 12 weeks after spinal anesthesia and multimodal analgesia for anterior cruciate ligament reconstruction.
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DOI：
10.1213/ane.0b013e318198d46e
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发表时间：
2009-04
影响因子：
5.7
通讯作者：
Kentor ML
中科院分区：
文献类型：
--
作者：
Williams BA;Dang Q;Bost JE;Irrgang JJ;Orebaugh SL;Bottegal MT;Kentor ML
我们之前报道，与多模式镇痛和安慰剂股神经周围输注相比，持续股神经周围镇痛可减轻前十字韧带重建后前 2 天内的运动疼痛（ACLR，n=270）。我们现在报告前瞻性收集的这些患者术后 7 天至 12 周的一般健康状况和膝关节功能结果。 ACLR 手术后 12 周内的 3 个时间点，患者完成了 SF-36 一般健康调查和膝关节结果调查 (KOS)。采用广义估计方程来评估患者报告的调查结果与 (i) 术前基线调查评分、(ii) 术后时间和 (iii) 3 个神经阻滞治疗组之间的关联。 217 名患者的数据已完成可供分析。在单变量和多元回归广义估计方程模型中，神经阻滞治疗组与术后SF-36和KOS评分均无相关性（均P≥0.05）。模型显示，SF-36 的身体成分总结（P < 0.0001）和 KOS 总分（P < 0.0001）随着手术后时间的推移而增加（改善），并且也受到基线分数的影响。脊髓麻醉和 ACLR 多模式镇痛后，神经阻滞治疗组无法预测术后 7 天至 12 周的 SF-36 或膝关节功能结果。需要进一步的研究来确定这些结论是否也适用于非标准化麻醉剂，或者包括全身麻醉和/或高剂量阿片类镇痛剂的麻醉剂。
We previously reported that continuous perineural femoral analgesia reduces pain with movement during the first 2 days after anterior cruciate ligament reconstruction (ACLR, n=270), when compared with multimodal analgesia and placebo perineural femoral infusion. We now report the prospectively collected general health and knee function outcomes in the 7 days to 12 weeks after surgery in these same patients. At 3 points during 12 weeks after ACLR surgery, patients completed the SF-36 General Health Survey, and the Knee Outcome Survey (KOS). Generalized Estimating Equations were implemented to evaluate the association between patient-reported survey outcomes and (i) preoperative baseline survey scores, (ii) time after surgery, and (iii) 3 nerve block treatment groups. Two-hundred-seventeen patients’ data were complete for analysis. In univariate and multiple regression Generalized Estimating Equations models, nerve block treatment group was not associated with SF-36 and KOS scores after surgery (all with P≥0.05). The models showed that the physical component summary of the SF-36 (P < 0.0001) and the KOS total score (P < 0.0001) increased (improved) over time after surgery and were also influenced by baseline scores. After spinal anesthesia and multimodal analgesia for ACLR, the nerve block treatment group did not predict SF-36 or knee function outcomes from 7 days to 12 weeks after surgery. Further research is needed to determine whether these conclusions also apply to a nonstandardized anesthetic, or one that includes general anesthesia and/or high-dose opioid analgesia.
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影响因子：
1.9
作者：
Johnson, DS;Smith, RB
通讯作者：
Smith, RB
影响因子：
6.7
作者：
Williams, BA;DeRiso, BM;Watkins, WD
通讯作者：
Watkins, WD
影响因子：
8.8
作者：
Williams, BA;Kentor, ML;Fu, FH
通讯作者：
Fu, FH
影响因子：
8.8
作者：
Capdevila, X;Barthelet, Y;d'Athis, F
通讯作者：
d'Athis, F
DOI：
10.2106/00004623-199808000-00006
发表时间：
1998-08-01
影响因子：
5.3
作者：
Irrgang, JJ;Snyder-Mackler, L;Harner, CD
通讯作者：
Harner, CD