Phenolic glycosides from Symplocos racemosa:: natural inhibitors of phosphodiesterase I

Phenolic glycosides from Symplocos racemosa:: natural inhibitors of phosphodiesterase I
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DOI:
10.1016/s0031-9422(03)00075-x
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发表时间:
2003-05-01
期刊:
影响因子:
3.8
通讯作者:
Choudhary, MI
Choudhary, MI
中科院分区:
生物学2区
文献类型:
--
作者:
Ahmad, VU;Abbasi, MA;Choudhary, MI

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从总状花环中分离得到一个新的酚苷,命名为苯甲酰唾液酸苷(1),以及一个已知的酚苷化合物,命名为唾液酸苷(2)。从该植物中还分离得到4个已知化合物,即β-香草素(3)、齐墩果酸(4)、β-谷甾醇(5)和β-谷甾醇糖苷(6)。化合物的结构鉴定主要基于1D和2D核磁共振分析,包括COSY、HMQC和HMBC关联。化合物1和2具有抑制蛇毒磷酸二酯酶的活性。(C)2003爱思唯尔科学有限公司。版权所有。
One new phenolic glycoside named benzoylsalireposide (1) along with one known phenolic glycoside named salireposide (2) have been isolated from Symplocos racemosa. Four other known compounds i.e. beta-amyrin (3), oleonolic acid (4), beta-sitosterol (5) and beta-sitosterol glycoside (6) were also isolated from this plant. The structure elucidation of the isolated compounds was based primarily on 1D- and 2D-NMR analysis, including COSY, HMQC, and HMBC correlations. The compound 1 and 2 showed inhibitory activity against snake venom phosphodiesterase I. (C) 2003 Elsevier Science Ltd. All rights reserved.