More scanning, but not zooming, is associated with diagnostic accuracy in evaluating digital breast pathology slides.
More scanning, but not zooming, is associated with diagnostic accuracy in evaluating digital breast pathology slides.
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DOI：
10.1167/jov.21.11.7
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发表时间：
2021-10-05
影响因子：
1.8
通讯作者：
Elmore JG
中科院分区：
文献类型：
--
作者：
Drew T;Lavelle M;Kerr KF;Shucard H;Brunyé TT;Weaver DL;Elmore JG
医学图像的诊断可以采用极其多样化的图像导航和视觉搜索策略。在肺结节的计算机断层扫描筛查中，不同的策略（称为扫描和钻孔）与放射科医生的临床经验和病变检测的准确性有关。在这里，我们检查了病理学家 (N = 92) 解释一组不同的乳腺活检图像的搜索模式和准确性之间的关联。虽然体积图像中深度的变化通过 z 平面的运动揭示了新的结构，但在数字病理学中，深度的变化与放大倍数的增加相关。因此，放射学中的“钻孔”在病理学中被称为“缩放”可能更合适。我们通过数字病理学幻灯片监测眼球运动和导航，以得出病理学家在 XY（扫描）和 Z（缩放）空间中移动的速度的指标。先前对眼球运动的深入研究将临床医生分为“扫描员”或“钻探员”。相比之下，我们发现临床医生在检查数字病理切片时扫描或缩放的倾向之间没有可靠的关联。因此，在当前的工作中，我们将扫描和缩放视为连续预测变量，而不是归类为“扫描仪”或“缩放器”。与之前的胸部体积图像研究相比，我们发现准确性和扫描速率之间存在显着关联，但缩放速率之间没有显着关联。这些发现表明两种图像格式的信息类型的相对价值和评论行为存在根本差异。我们的数据表明，病理学家通过扫描给定的深度平面来收集关键信息，而放射科医生则通过深度钻探来询问关键特征。
Diagnoses of medical images can invite strikingly diverse strategies for image navigation and visual search. In computed tomography screening for lung nodules, distinct strategies, termed scanning and drilling, relate to both radiologists’ clinical experience and accuracy in lesion detection. Here, we examined associations between search patterns and accuracy for pathologists (N = 92) interpreting a diverse set of breast biopsy images. While changes in depth in volumetric images reveal new structures through movement in the z-plane, in digital pathology changes in depth are associated with increased magnification. Thus, “drilling” in radiology may be more appropriately termed “zooming” in pathology. We monitored eye-movements and navigation through digital pathology slides to derive metrics of how quickly the pathologists moved through XY (scanning) and Z (zooming) space. Prior research on eye-movements in depth has categorized clinicians as either “scanners” or “drillers.” In contrast, we found that there was no reliable association between a clinician's tendency to scan or zoom while examining digital pathology slides. Thus, in the current work we treated scanning and zooming as continuous predictors rather than categorizing as either a “scanner” or “zoomer.” In contrast to prior work in volumetric chest images, we found significant associations between accuracy and scanning rate but not zooming rate. These findings suggest fundamental differences in the relative value of information types and review behaviors across two image formats. Our data suggest that pathologists gather critical information by scanning on a given plane of depth, whereas radiologists drill through depth to interrogate critical features.
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影响因子：
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作者：
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通讯作者：
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