RENIN-LIKE SUBSTANCE IN PLACENTA AND UTERUS OF RABBIT.
RENIN-LIKE SUBSTANCE IN PLACENTA AND UTERUS OF RABBIT.
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兔胎盘和子宫中的类肾素物质。
DOI：
10.1016/s0140-6736(64)91637-x
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发表时间：
1964
期刊：
影响因子：
168.9
通讯作者：
M. Berger
中科院分区：
文献类型：
--
作者：
F. Gross;G. Schaechtelin;M. Ziegler;M. Berger
讨论结果表明，免疫的脾细胞延缓了 Landschutz 肿瘤的生长。免疫方式很重要，目前活肿瘤细胞是最好的抗原。尽管腹水发生的延迟和生存时间的延长是惊人的，但这在很大程度上可以归因于肿瘤转变为实性和浸润性形式。治疗 60 天后用氯仿处死的小鼠的尸检和详细显微镜检查显示肿瘤不存在或不明显。因此，淋巴细胞很可能除了具有细胞毒性外，还具有细胞毒性。
DISCUSSIONThe results show that immunised spleen cells retard the growth of the Landschutz tumour. The manner of immunisation is important, and at present live tumour cells make the best antigen. Although the delay in onset of ascites and prolongation of survival-time is striking, this can largely be accounted for by the conversion of the tumour to a solid and infiltrative form. Postmortem and detailed microscopic examination of mice killed with chloroform 60 days after treatment has shown tumour to be either absent or inconspicuous. Accordingly it is probable that the lymphoid cells have a cytotoxic besides