Implementation of a colorectal cancer screening intervention in Malaysia (CRC-SIM) in the context of a pandemic: study protocol.
Implementation of a colorectal cancer screening intervention in Malaysia (CRC-SIM) in the context of a pandemic: study protocol.
复制标题
DOI：
10.1136/bmjopen-2021-058420
复制
发表时间：
2022-09-01
期刊：
影响因子：
2.9
通讯作者：
Donnelly, Michael
中科院分区：
文献类型：
--
作者：
Schliemann, Desiree;Ramanathan, Kogila;Tamin, Nor Saleha Binti Ibrahim;O'Neill, Ciaran;Cardwell, Christopher R.;Ismail, Roshidi;Nanu, Prathibha;Ghazali, Ahmad Nizal bin Mohd;Kee, Frank;Su, Tin Tin;Donnelly, Michael
结直肠癌（CRC）是马来西亚第二大常见癌症，病例通常发现较晚。提高筛查率是降低癌症分期和改善患者预后的关键。本研究的目的是在2019冠状病毒病大流行的背景下，制定、实施和评估一项干预措施，以提高马来西亚CRC筛查的接受程度。评价将包括确定实施和提供干预措施的预算影响。实施研究逻辑模型指导了研究的发展，实施结果措施由“覆盖、有效性、采用、实施和维护”（RE-AIM）框架提供信息。马来西亚的这项CRC筛查干预措施使用家庭检测和数字、小型媒体传播来提高CRC筛查的接受程度。将从东南亚社区观测站（SEACO）的数据库中随机抽取780名居住在马来西亚西加马地区50-75岁的人作为样本。参与者将收到一个筛查包，以及一段当地医生安全进行粪便检查的WhatsApp视频，并将检查结果的照片发送到一个保密的手机号码。赛会职员会通知参加者结果。将收集有关随访诊所出勤率、随后的医院检查和结果的定量数据。逻辑回归将用于调查影响筛查完成的变量，我们将对干预措施及其实施进行预算影响分析。从参与者和利益相关者的角度对干预实施的定性数据进行专题分析。蒙纳士大学人类研究伦理委员会（MUHREC ID: 29107）和医学审查与伦理委员会（参考编号：21-02045-O7G(2)）已给予伦理批准。结果将通过出版物、会议和社区参与活动传播。马来西亚国家医学研究登记处：21-02045-O7G(2)。
Colorectal cancer (CRC) is the second most common cancer in Malaysia and cases are often detected late. Improving screening uptake is key in down-staging cancer and improving patient outcomes. The aim of this study is to develop, implement and evaluate an intervention to improve CRC screening uptake in Malaysia in the context of the COVID-19 pandemic. The evaluation will include ascertaining the budgetary impact of implementing and delivering the intervention. The implementation research logic model guided the development of the study and implementation outcome measures were informed by the 'Reach, Effectiveness, Adoption, Implementation and Maintenance' (RE-AIM) framework. This CRC screening intervention for Malaysia uses home-testing and digital, small media, communication to improve CRC screening uptake. A sample of 780 people aged 50–75 years living in Segamat district, Malaysia, will be selected randomly from the South East Asia Community Observatory (SEACO) database. Participants will receive a screening pack as well as a WhatsApp video of a local doctor to undertake a stool test safely and to send a photo of the test result to a confidential mobile number. SEACO staff will inform participants of their result. Quantitative data about follow-up clinic attendance, subsequent hospital tests and outcomes will be collected. Logistic regression will be used to investigate variables that influence screening completion and we will conduct a budget impact-analysis of the intervention and its implementation. Qualitative data about intervention implementation from the perspective of participants and stakeholders will be analysed thematically. Ethics approval has been granted by Monash University Human Research Ethics Committee (MUHREC ID: 29107) and the Medical Review and Ethics Committee (Reference: 21-02045-O7G(2)). Results will be disseminated through publications, conferences and community engagement activities. National Medical Research Register Malaysia: 21-02045-O7G(2).
登录
查看更多内容
DOI：
10.1016/s1473-3099(21)00197-3
发表时间：
2021-09
期刊：
The Lancet. Infectious diseases
影响因子：
--
作者：
Boum Y;Eyangoh S;Okomo MC
通讯作者：
Okomo MC
DOI：
10.1186/1748-5908-4-50
发表时间：
2009-08-07
期刊：
Implementation science : IS
影响因子：
--
作者：
Damschroder LJ;Aron DC;Keith RE;Kirsh SR;Alexander JA;Lowery JC
通讯作者：
Lowery JC
影响因子：
3.2
作者：
Manji K;Hanefeld J;Vearey J;Walls H;de Gruchy T
通讯作者：
de Gruchy T
影响因子：
9.3
作者：
Moss, S.;Ancelle-Park, R.;Brenner, H.
通讯作者：
Brenner, H.
影响因子：
3.8
作者：
Schliemann D;Ramanathan K;Matovu N;O'Neill C;Kee F;Su TT;Donnelly M
通讯作者：
Donnelly M