SUB-PERIOSTEAL EXPANSION AND CORTICAL REMODELING OF THE HUMAN FEMUR AND TIBIA WITH AGING
SUB-PERIOSTEAL EXPANSION AND CORTICAL REMODELING OF THE HUMAN FEMUR AND TIBIA WITH AGING
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DOI：
10.1126/science.7112107
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发表时间：
1982-01-01
期刊：
影响因子：
56.9
通讯作者：
HAYES, WC
中科院分区：
文献类型：
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作者：
HAYES, WC
在美国西南部的考古样本中记录了[人类]股骨和胫骨横截面中骨膜下尺寸和面积二阶矩（弯曲和扭转刚度的测量）随老化而增加。[考古学样本的优势在于，与现代解剖室的收藏相比，它们在遗传和环境上更具有同质性。也存在显著差异的横截面网站之间和性别之间的皮质重塑随着年龄的增长模式。这些差异似乎与股骨和胫骨不同区域的应力或应变水平的变化有关，这些变化是由下肢的体内机械载荷引起的。
Increases with aging in subperiosteal dimensions and 2nd moments of area (measures of bending and torsional rigidity) in [human] femoral and tibial cross sections are documented in an archaeological sample from the American [USA] Southwest. [Archaeological samples have the advantage of being generally more genetically and environmentally homogeneous than modern dissection room collections.] Significant differences between cross-sectional sites and between sexes in the pattern of cortical remodeling with age are also present. These differences appear to be related to variations in the stress or strain levels in different regions of the femur and tibia which result from in vivo mechanical loadings of the lower limb.