X-inactivation: it takes two to count.

X-inactivation: it takes two to count.
复制标题

X-失活:需要两个来计数。

DOI:
10.1016/j.cub.2008.01.039
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发表时间:
2008
期刊:
Current biology : CB
影响因子:
--
通讯作者:
Panning,Barbara
Panning,Barbara
中科院分区:
--
文献类型:
--
作者:
Royce-Tolland,Morgan;Panning,Barbara

文献摘要

相似文献

哺乳动物通过沉默雌性细胞中的一条X染色体来平衡X连锁基因的剂量,这一过程始于计数X染色体的数量。最近的报告表明同源X染色体配对可能是沉默的先决条件,通过确保沉默仅发生在具有两条X染色体的细胞中,为计数提供了基础。
Mammals balance X-linked gene dosage by silencing one X chromosome in female cells, a process that begins with counting the number of X chromosomes. Recent reports suggest homologous X chromosome pairing may be a prerequisite for silencing, providing a basis for counting by ensuring that silencing only occurs in cells with two X chromosomes.