An ESIPT-induced NIR fluorescent probe to visualize mitochondrial sulfur dioxide during oxidative stress in vivo
An ESIPT-induced NIR fluorescent probe to visualize mitochondrial sulfur dioxide during oxidative stress in vivo
复制标题
ESIPT 诱导的近红外荧光探针可在体内氧化应激过程中可视化线粒体二氧化硫
DOI：
10.1039/d0cc07398a
复制
发表时间：
2021-01-16
影响因子：
4.9
通讯作者：
Yin, Caixia
中科院分区：
文献类型：
--
作者：
Ren, Haixian;Huo, Fangjun;Yin, Caixia
Based on the change in electron distribution of the benzopyrylium unit before and after sulfite addition, a 2-(2 '-hydroxyphenyl)benzothiazole (HBT)-based fluorophore generated the excited state intramolecular proton transfer (ESIPT) process with a near-infrared enhanced emission at 836 nm and a large Stokes shift (286 nm). The probe was applied to image SO2 derivatives in cells and mice. Our data will provide new ideas for the development of ESIPT-based fluorescence probe with longer wavelength emission.
