Pulse oximetry in sickle cell anemia
Pulse oximetry in sickle cell anemia
复制标题
DOI：
10.1097/00003246-200109000-00025
复制
发表时间：
2001-09-01
影响因子：
8.8
通讯作者：
Johnson, A
中科院分区：
文献类型：
--
作者：
Fitzgerald, RK;Johnson, A
目标。目的：确定小儿镰状细胞性贫血患者脉搏血氧测定是否准确，是否与动脉血气饱和度相关。设计：前瞻性，比较研究，使用镰状细胞性贫血患者的方便样本，同时进行动脉血气采样和脉搏血氧测定。背景：儿童纪念医院，伊利诺伊州芝加哥市的一家大型三级儿科医院。患者从急诊科和儿科重症监护室选择。患者：连续24例镰状细胞性贫血患者，同时进行动脉血气采样和脉搏血氧测定。测量结果及主要结果：24例患者共70例脉搏血氧仪和血气对同时采样。采用每位患者初始脉氧仪/血气对进行统计分析。3例患者有静脉样本，排除比较，留下21对动脉血气/脉搏血氧仪分析。脉搏血氧仪与血氧仪测量的动脉饱和度相关性良好（r(2) = 0.74）。脉搏血氧计明显低估了饱和度，平均低估了-1.6%（95%置信区间，-0.3至-3；p = .03）。结论：镰状细胞性贫血患者脉搏血氧测定与血氧饱和度的相关性良好。脉搏血氧测定法明显低估了真实动脉饱和度，但临床偏差不显著。脉搏血氧仪可以可靠地估计镰状细胞性贫血患者的动脉血氧饱和度。
Objectives. To determine whether pulse oximetry is accurate and if it correlates with arterial blood gas saturation in pediatric patients with sickle cell anemia.Design: Prospective, comparative study using a convenience sample of patients with sickle cell anemia who had simultaneous arterial blood gas sampling and pulse oximetry.Setting, Children's Memorial Hospital, a large tertiary care pediatric hospital in Chicago, IL.Patients selected from the emergency department and the pediatric intensive care unit. Patients: Twenty-four consecutive patients with sickle cell anemia who had simultaneous arterial blood gas sampling and pulse oximetry.Measurements and Main Results: Twenty-four patients had a total of 70 simultaneous pulse oximeter and blood gas pair samples. Each patient's initial pulse oximeter/blood gas pair was used in the statistical analysis. Three patients had venous Samples and were excluded from comparison, leaving 21 arterial blood gas/pulse oximeter pairs for analysis. The pulse oximeter correlated well with the cooximeter-measured arterial saturation (r(2) = .74). The pulse oximeter significantly underestimated saturation by a mean of -1.6% (95% confidence interval, -0.3 to -3; p = .03).Conclusions: Pulse oximetry correlates well with cooximeter-measured saturation in patients with sickle cell anemia. Pulse oximetry significantly underestimates true arterial saturation, but the bias is clinically insignificant. Pulse oximetry can be used reliably to estimate the arterial oxygen saturation in patients with sickle cell anemia.