Magnetic separation hydroxynitrile glucoside of Orostachys malacophyllus

Magnetic separation hydroxynitrile glucoside of Orostachys malacophyllus
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DOI:
10.1016/j.microc.2021.106223
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发表时间:
2021-04
影响因子:
4.8
通讯作者:
Xiumei Yin;Jingdong Zhang;Sihong Wang;Donghao Li
Xiumei Yin;Jingdong Zhang;Sihong Wang;Donghao Li
中科院分区:
化学2区
文献类型:
--
作者:
Xiumei Yin;Jingdong Zhang;Sihong Wang;Donghao Li

文献摘要

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双利是一种分离效率的策略。通过选择合适的方法,可以有效地提取植物提取物中的小分子。采用CCK-8方法指导生物测定。采用磁分离作为提取探针来捕获和富集有效的细胞毒性成分。硼酸盐功能化磁性固体(BFMS)的两个目的是包裹疏水性成分和从O的乙酸乙酯提取物中留下亲水性成分。 malacophyllus,幸运的是,获得了(R)-lotastralin、1-O-α-D-吡喃葡萄糖基-β-D-吡喃果糖和3-O-α-D-吡喃葡萄糖基-β-D-呋喃果糖。结果,O. Malacophyllusis 众所周知,它们还含有羟基腈葡萄糖苷。这为植物分析中富集羟基腈葡萄糖苷提供了一条途径。
A double benefit is a kind of strategy for separate efficiency. By selecting the appropriate method, the small molecule in plant extracts can be effectively extracted. CCK-8 method was employed to bioassay-guide. Magnetic separation was adopted as extraction probe to capture and enrich potent cytotoxicity constituent. Borate functionalized magnetic solid (BFMS) was performed for two purposes to wrap hydrophobic and to leave hydrophilic component from the ethyl acetate extract ofO. malacophyllus, fortunately, (R)-lotastralin, 1-O-alpha-D-glucopyranosyl-beta-D-fructopyranose and 3-O-alpha-D-glucopyranosyl-beta-D-fructo furanose was obtained. As a result,O. malacophyllusis much well-known that they also contain hydroxynitrile glucoside. This provides a route to enrich hydroxynitrile glucoside in plant analysis.