Correlation of blood pressure, obesity, and adherence to the Mediterranean diet with indices of arterial stiffness in children
Correlation of blood pressure, obesity, and adherence to the Mediterranean diet with indices of arterial stiffness in children
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DOI：
10.1007/s00431-012-1735-3
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发表时间：
2012-09-01
影响因子：
3.6
通讯作者：
Lydaki, Danai
中科院分区：
文献类型：
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作者：
Lydakis, Charalampos;Stefanaki, Evaggelia;Lydaki, Danai
这项研究的目的是评估肥胖、血压(BP)和饮食习惯(坚持地中海饮食)与儿童动脉僵硬指数(AS)相关的假设。277名12岁的儿童使用R6.5 PulsecorA(R)监护仪进行了测量，该监护仪在短时间内使用保持在高于收缩压的上臂BP袖带进行测量。以肱动脉增粗指数(AI)、外周脉压/中心脉压(PPP/CPP)比值、反射波传导时间/高度比值作为AS的指标。坚持地中海饮食的程度通过KIDMED指数进行评估，该指数包括关于特定饮食习惯的16个问题。43%的儿童超重和肥胖。超重和肥胖儿童的PPP/CPP和KIDMED评分显著低于体重指数(BMI)正常儿童。在多因素回归模型中，AS指数与平均外周血压、心率、身高相关，而BMI与PPP/CPP独立相关。除肥胖外，KIDMED指数与AI也呈负相关。结论：肥胖和坚持地中海饮食模式是与12岁儿童AS指数独立相关的因素。
The aim of the study was to assess the hypothesis that obesity, blood pressure (BP), and dietary habits (adherence to the Mediterranean diet) are related to indices of arterial stiffness (AS) in childhood. Two hundred and seventy-seven children aged 12 years were measured with the R6.5 PulsecorA (R) monitor, which performs measurements using an upper arm BP cuff held at above systolic pressure for a short time. The augmentation index (AI) in the brachial artery, the peripheral pulse pressure to central pulse pressure (PPP/CPP) ratio, and the reflected wave transit time to height ratio were used as indices of AS. The degree of adherence to the Mediterranean diet was assessed by the KIDMED index which includes 16 questions on specific dietary habits. Forty-three percent of the children were overweight and obese. Overweight and obese children had significantly lower PPP/CPP and KIDMED score in comparison to children with normal body mass index (BMI). In multivariate regression models, indices of AS were related to mean peripheral BP, heart rate, and height, while BMI had an independent correlation to PPP/CPP. The KIDMED index also had a negative correlation with AI independently of obesity. Conclusion: Obesity and adherence to the Mediterranean diet patterns are factors related independently to indices of AS even in 12-year-old children.