Phospholipid metabolism and membrane dynamics
Phospholipid metabolism and membrane dynamics
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DOI：
10.1016/s0955-0674(96)80032-9
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发表时间：
1996-08-01
影响因子：
7.5
通讯作者：
Bankaitis, VA
中科院分区：
文献类型：
--
作者：
Alb, JG;Kearns, MA;Bankaitis, VA
遗传学和生物化学的方法正在揭示特定磷脂代谢途径的独特生理功能和磷脂在细胞内室之间流动的机制。特别是，磷脂酰肌醇转移蛋白最近被发现发挥迷人的和意想不到的作用，在协调磷脂代谢与囊泡贩运和信号转导反应。
Genetic and biochemical approaches are shedding new light on the distinct physiological functions of specific phospholipid metabolic pathways and the mechanisms by which phospholipids are mobilized between intracellular compartments. In particular, phosphatidylinositol-transfer proteins have recently been revealed to play fascinating and unanticipated roles in the coordination of phospholipid metabolism with vesicle-trafficking and signal-transducing reactions.